Have you ever wondered what causes aging and how to slow it down?

As we age, we lose the ability to synthesize proteins – the building blocks of the human body and brain. Increased supplementation with peptides can decrease the rate of aging through enhanced protein production with benefits that can be experienced in the body and mind.

This article is going to break down all the biological concepts behind peptide bioregulators. You will also learn how to supplement your healthy lifestyle, regulate metabolism, decrease the signs of aging and improve brain function.

What are peptide bioregulators?

The word peptide is derived from the Greek word “peptos” which means “digested”. The term describes short chains of amino acids linked together by peptide bonds, also known as polypeptides.

Polypeptides that contain roughly fifty or more amino acids are known as proteins. As we get older, we can develop peptide deficiencies in tissues throughout our body with consequences on tissue regeneration.

Bioactive Peptides

Proteins contain approximately 50 or more protein-building amino acids. Bioactive peptides are shorter protein fragments of 2-20 amino acids in length. Like proteins, bioactive peptides can affect a variety of functions in the body with many properties as follows:

Antioxidant Properties

One of the major causes of human disease is oxidation. Peptides obtained from substances such as milk protein have been shown to contain antioxidant properties. A protein in milk called casein produces both water and fat-based antioxidant activity. Other peptides, such as those derived from soy have also demonstrated some antioxidant activity.

Immune System Modulation

Research demonstrates that some peptides have anti-inflammatory properties. Inflammation is a key cause of many diseases and can have various adverse effects throughout the body.  Peptides from ovotransferrin, a protein found in egg whites, are suspected of inhibiting the proliferation of disease-fighting white blood cells in the spleens of mice. Accordingly, rice and soybean peptides may trigger non-specific immune defence systems that combat illness in the body.

Metabolic effects

Metabolism refers to chemical reactions in the body that sustain life such as:

  • Conversion of food to energy to power cell function
  • Conversion of food to build proteins, fats, carbohydrates and nucleic acids
  • Waste elimination from the body

Some bioactive peptides are involved in metabolic regulation. Since peptides decrease as we age, their reduction can lead to several conditions that include obesity, diabetes, elevated triglycerides and hypertension.

Peptide Bioregulators Studies

Much of the research into bio regulating peptide therapy was conducted by Professor Vladimir Khavinson, Treasurer of the European region of the International Association of Gerontology and Geriatrics. He is widely credited with the discovery of peptide bioregulators and the development of bio regulating peptide therapy. Professor Khavinson has also overseen experimental and clinical peptide bioregulator studies over the course of his career.

Professor Khavinson engaged extensively in research into the mechanisms of ageing. He specifically studied the role of peptides through the design of both clinical and preclinical peptide geroprotector studies. His investigation over four decades resulted in several methods using peptide bioregulators to increase the human lifespan and slow down the process of ageing. Along with introducing a wide range of peptide supplements throughout his career, Professor Khavinson created six peptide-based supplements available today, along with two books that include “Peptides and Ageing” (NEL, 2002) and “Gerontological Aspects of Genome Peptide Regulation”. An extensive review of his research is available through the Khavinson Peptides International Research Foundation.

Benefits of Peptide Bioregulators

Peptide bioregulation is accomplished through food and supplementation. Research over several decades has suggested that the use of biopeptide supplements can produce the following effects:

  • More energy and increased capacity for physical activity
  • Cardiovascular system rejuvenation and reduced rate of ageing
  • Metabolism regulation
  • Enhanced brain function
  • Viral disease resistance

There are several categories of biopeptide regulator supplements that include:

Skincare Peptides

According to Vichy consulting dermatologist Erin Gilbert, M.D., specific peptides found in skin creams and topical lotions can send signals to your cells to produce more collagen. Since collagen is an essential building block of youthful skin, skincare peptides can help promote a smoother appearance.

Weight Loss Peptides

According to New York City-based physician Dr Paulvin, several peptides can aid weight loss through the following effects:

  • Promoting resistance to metabolic stress
  • Enhanced lipid beta-oxidation
  • Improved glucose uptake
  • Increase growth hormones
  • Increase fat oxidation
  • Enhance muscle tissue growth

Hair Growth Peptides

Women swinging her hair

Scientific research has shown that water-soluble peptides derived from egg yolks stimulate peptide production and human hair follicle dermal papilla cell growth. The researchers hypothesized that chicken eggs contain these key hair growth factors because hair grows in chickens between the fourteenth and fifteenth hatching days. As a result, the researchers named this water-soluble egg yolk peptide “Hair Growth Peptide” (HGP).

Other Anti-Aging Supplements

Other supplements like Nuchido TIME+ can work to combat the sign of ageing.

Developed by a team of scientists and systems pharmacologists at Nuchido Laboratories, Nuchido TIME+ supplies Nicotinamide Adenine Dinucleotide (NAD+) to the body.

NAD+ is a natural molecule found in every cell in the body. Research by Nuchido Laboratories suggests that it facilitates metabolism and cellular repair for an overall anti-ageing effect.


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