What is Citicoline?
Citicoline, also known as CDP-Choline (Cytidine Diphosphate Choline), is a powerful substance composed of two components: choline and cytidine. This compound combines the benefits of both substances into one, making it a versatile supplement for brain health.ย ย
Citicoline is a naturally occurring substance in the body. It is produced as an intermediate product in the biosynthesis of phospholipids, which are essential for the structure and function of cell membranes. Although the body can produce Citicoline on its own, taking Citicoline through supplements can help boost levels and offer additional benefits for overall health.
Citicoline becomes Choline and Cytidine
When Citicoline (CDP-Choline) is ingested, it is quickly absorbed and broken down into two key components: choline and cytidine. Choline is essential for the production of acetylcholine, a neurotransmitter crucial for memory and learning. Cytidine is converted into uridine, which plays a role in neuronal development and plasticity. This breakdown and conversion ensure that Citicoline effectively contributes to enhanced cognitive function, neuroprotection, and recovery after brain injury.
Health Benefits of Choline:ย ย
Choline contributes to:ย ย
- Normal homocysteine metabolism. *
- Normal fat metabolism. *
- The maintenance of normal liver function. *
Figure 1: Citicoline becomes Choline and Cytidine.ย ย
What is Cytidine?ย ย
Cytidine is a nucleoside, a building block of RNA (ribonucleic acid), consisting of the nucleobase cytosine bound to a ribose sugar. It plays a crucial role in cell biology, as it is involved in the coding, decoding, regulation, and expression of genes. Cytidine is essential for RNA synthesis and helps promote neuronal communication and plasticity in the brain, contributing to cognitive functions and recovery after brain injury.
Why is it better to take Citicoline instead of direct Choline?ย ย
Citicoline (CDP-Choline) offers significant advantages over direct choline intake due to its higher bioavailability and dual-action components. Upon ingestion, Citicoline is efficiently absorbed and broken down into choline and cytidine, with choline supporting the production of the neurotransmitter acetylcholine and cytidine converting into uridine, which aids in neuronal development and brain plasticity.
CDP-Choline Dosageย ย
CDP-choline is typically taken in doses ranging from 500 mg per day to 2000 mg per day. It can be taken all at once, but it works best when divided into two doses, spaced 8-12 hours apart. As with all nootropics, it is recommended to start with a low dose and increase it as needed. Some users report excellent results with just 500 mg per day, while others notice no effects until they reach up to 2,000 mg per day. It is recommended to start with 250 mg twice a day for the first few weeks and then increase the dosage if the desired results are not achieved. CDP-Choline may be absorbed slightly better when taken on an empty stomach. However, this is not necessary. If you experience nausea or an upset stomach, it’s best to take CDP-choline with a small meal.
Combining Citicoline with Alpha GPCย ย
Citicoline is often combined with Alpha GPC for powerful cognitive support. Citicoline promotes the production of phosphatidylcholine, which is important for brain cell membranes, while Alpha GPC stimulates the production of acetylcholine, an important neurotransmitter for memory and learning. Together, these two supplements enhance mental clarity, focus, and overall brain health.
Buying Citicoline from Cerebraย ย
Our Citicoline capsules are of the highest quality and sourced from reliable suppliers. We ensure that our products meet strict quality standards so you can confidently purchase and experience their benefits. Our products are batch-tested in the lab.
*Disclaimer:* Health claim pending European approval.
