Benefits of Magnesium L-Threonate

Improves sleep and reduces anxiety

A recent study(1) on humans has shown improvements in the cognitive function of human brains when supplemented with magnesium l-threonate, resulting in better sleep quality and reduction of anxiety.

Better brain function

Magnesium l-threonate has been shown to improve brain function through its effect on brain synapses.(1) 

A synapse is a small gap at the end of a neuron that allows a signal to pass from one neuron to the next. As brains age, the density of these synapses decreases however research has shown that magnesium l-threonate increases synapse density and improves brain function.

Reverses brain aging

Magnesium l-threonate rapidly crosses the blood-brain barrier resulting in regeneration of brain tissues.(1-4)

Memory Improvement

Better brain function means improved memory. Supplementation with magnesium l-threonate has been shown to improve recall and slow age-related memory decline.(5)

Side effects

Magnesium promotes relaxation which may result in loose stools when ingesting large amounts. 

References

1. Liu G, Weinger JG, Lu ZL, et al. Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J Alzheimers Dis. 2016;49(4):971-90.
2. Slutsky I, Abumaria N, Wu LJ, et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010;65(2):165-77.
3. Abumaria N, Yin B, Zhang L, et al. Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. J Neurosci. 2011;31(42):14871-81.
4. Li W, Yu J, Liu Y, et al. Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model. Mol Brain. 2014;7:65.
5. Billard, J. M. (2006). Ageing, hippocampal synaptic activity and magnesium. Magnesium Research, 19(3), 199–215. https://doi.org/10.1684/mrh.2006.0063