Get to the source of fatigue issues. Sulbutiamine treats symptoms of fatigue and lack of concentration by increasing levels of vitamin B1 in the brain. 

A synthetic derivative of thiamine, Sulbutiamine was discovered in Japan in the 1950s in order to treat thiamine deficiency and its associated disorders related to fatigue and weakness. 

Sulbutiamine was also extensively studied in the 1980s and 1990s to address thiamine deficiency and its role in age-associated cognitive decline causing memory issues and other brain disorders.


Benefits of Sulbutiamine

Vitamin B1/Thiamine is essential for mitochondrial membrane development and synaptosomal membrane function, an important aspect of brain development.(1) 

Sulbutiamine, it’s fat-soluble synthetic version has been shown to have effects in connection with the following conditions:

  • Weakness or fatigue(2)
  • Sports performance enhancement(3)
  • MS-related fatigue symptoms(4)

Side effects

Side effects have been reported in clinical trials including bladder infections, pain due to arthritis, digestive issues like diarrhea, abdominal pain, back pain, breathing issues (asthma, bronchitis), insomnia, constipation, gastroenteritis, diffuse pain, sinusitis, headache, kidney pain, vertigo, and sore throat.(5)

Dosage per day: 400 – 1000 mg per day
Effect onset: 30 – 60 minutes

As Sulbutiamine is fat-soluble, be sure to take it with a fat source – this ensures that your body absorbs it. Sulbutiamine is thought to have mild stimulant effects, so you might not want to take it too late into the night to prevent sleep interference.

Tolerance can be an issue with Sulbutiamine. You may, therefore, find it beneficial to cycle on and off the supplement. A popular way of cycling Sulbutiamine is 3 days on, 1 day off – but you’re free to experiment until you find a cycle that best works for you.

Sulbutiamine, cellulose (vegetarian capsules)

User discretion is advised. Individuals from the following groups and/or any other groups at risk should consult with a doctor prior to taking this or any other medication:

  • Pregnancy or lactating women
  • Children under the age of 12
  • Individuals with kidney problems
  • Individuals with heart and/or blood pressure problems
  • Immunocompromised individuals

Additional Notes

  • Do not exceed the recommended dose
  • Keep out of reach of children
  • Store in cool dark conditions
  • Do not consume past the expiry date
  • Suitable for vegans/vegetarians
  • This product and its statements have not been evaluated by the FDA or any other regulatory body
  • This product is a dietary supplement and is not a substitute for a varied and balanced diet and/or healthy lifestyle


Write a review for this product

Karola  | Jun 13, 2020

This product helped with my depression, and social shyness - I use it frequently

Jolanta Victor  | Jul 09, 2020

It improves my mood and lowers anxiety

Thank You for signing up!

Use coupon code newsignup15 to get a 15% discount on your next order of €25 or more